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Retinoblastoma Protein Transcriptional Repression through Histone Deacetylation of a Single Nucleosome

The retinoblastoma protein, pRb, controls transcription through recruitment of histone deacetylase to particular E2F-responsive genes. We determined the acetylation level of individual nucleosomes present in the cyclin E promoter of RB(+/+) and RB(−/−) mouse embryo fibroblasts. We also determined th...

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Bibliografski detalji
Izdano u:Mol Cell Biol
Glavni autori: Morrison, Ashby J., Sardet, Claude, Herrera, Rafael E.
Format: Artigo
Jezik:Inglês
Izdano: Taylor & Francis 2002
Teme:
Online pristup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC133558/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11784861/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.22.3.856-865.2002
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