Retinoblastoma Protein Transcriptional Repression through Histone Deacetylation of a Single Nucleosome
The retinoblastoma protein, pRb, controls transcription through recruitment of histone deacetylase to particular E2F-responsive genes. We determined the acetylation level of individual nucleosomes present in the cyclin E promoter of RB(+/+) and RB(−/−) mouse embryo fibroblasts. We also determined th...
में बचाया:
| में प्रकाशित: | Mol Cell Biol |
|---|---|
| मुख्य लेखकों: | , , |
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
Taylor & Francis
2002
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC133558/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11784861/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.22.3.856-865.2002 |
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