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Heparanase modulates Shh and Wnt3a signaling in human medulloblastoma cells

The pathogenesis of medulloblastoma (MB), the most common and aggressive brain tumor in children, is poorly understood. MB tumors respond to factors secreted by cerebellar Purkinje neurons, such as Sonic hedgehog (Shh) and Wingless-type MMTV integration site family member 3a (Wnt3a). Understanding t...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: RIDGWAY, LON D., WETZEL, MICHAEL D., MARCHETTI, DARIO
Format: Artigo
Sprache:Inglês
Veröffentlicht: D.A. Spandidos 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3063606/
https://ncbi.nlm.nih.gov/pubmed/21442027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2010.189
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