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Heparanase modulates Shh and Wnt3a signaling in human medulloblastoma cells

The pathogenesis of medulloblastoma (MB), the most common and aggressive brain tumor in children, is poorly understood. MB tumors respond to factors secreted by cerebellar Purkinje neurons, such as Sonic hedgehog (Shh) and Wingless-type MMTV integration site family member 3a (Wnt3a). Understanding t...

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Detalhes bibliográficos
Main Authors: RIDGWAY, LON D., WETZEL, MICHAEL D., MARCHETTI, DARIO
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3063606/
https://ncbi.nlm.nih.gov/pubmed/21442027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2010.189
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