Medulloblastoma: clinicopathological correlates of SHH, WNT, and non-SHH/WNT molecular subgroups

Medulloblastoma is heterogeneous, being characterized by molecular subgroups that demonstrate distinct gene expression profiles. Activation of the WNT or SHH signaling pathway characterizes two of these molecular subgroups, the former associated with low-risk disease and the latter potentially targe...

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Hauptverfasser: Ellison, David W., Dalton, James, Kocak, Mehmet, Nicholson, Sarah Leigh, Fraga, Charles, Neale, Geoff, Kenney, Anna M., Brat, Dan J., Perry, Arie, Yong, William H., Taylor, Roger E., Bailey, Simon, Clifford, Steven C., Gilbertson, Richard J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3519926/
https://ncbi.nlm.nih.gov/pubmed/21267586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-011-0800-8
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