Lanean...

RIM proteins tether Ca(2+)-channels to presynaptic active zones via a direct PDZ-domain interaction

At a synapse, fast synchronous neurotransmitter release requires localization of Ca(2+)-channels to presynaptic active zones. How Ca(2+)-channels are recruited to active zones, however, remains unknown. Using unbiased yeast two-hybrid screens, we here identify a direct interaction of the central PDZ...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Kaeser, Pascal S., Deng, Lunbin, Wang, Yun, Dulubova, Irina, Liu, Xinran, Rizo, Josep, Südhof, Thomas C.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2011
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3063406/
https://ncbi.nlm.nih.gov/pubmed/21241895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2010.12.029
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!