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RIM C(2)B domains target presynaptic active zone functions to PIP(2)-containing membranes
Rapid and efficient synaptic vesicle fusion requires a pool of primed vesicles, the nearby tethering of Ca(2+) channels, and the presence of the phospholipid PIP(2) in the target membrane. While the presynaptic active zone mediates the first two requirements, it is unclear how fusion is targeted to...
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| Pubblicato in: | Neuron |
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| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5910229/ https://ncbi.nlm.nih.gov/pubmed/29606581 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2018.03.011 |
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