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RIM determines Ca(2+) channel density and vesicle docking at the presynaptic active zone

At presynaptic active zones, neurotransmitter release is initiated by the opening of voltage-gated Ca(2+) channels close to docked vesicles. The mechanisms that enrich Ca(2+) channels at active zones are, however, largely unknown, possibly because of the limited presynaptic accessibility of most syn...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Han, Yunyun, Kaeser, Pascal S., Südhof, Thomas C., Schneggenburger, Ralf
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3259453/
https://ncbi.nlm.nih.gov/pubmed/21262468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2010.12.014
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