RIM1 confers sustained activity and neurotransmitter vesicle anchoring to presynaptic Ca2+ channels

The molecular organization of presynaptic active zones (AZs) is central to neurotransmitter release triggered by depolarization-induced Ca(2+) influx. Here, we demonstrate a novel interaction between AZ components, RIM1 and voltage-dependent Ca(2+) channels (VDCCs), that controls neurotransmitter re...

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Detalhes bibliográficos
Main Authors: Kiyonaka, Shigeki, Wakamori, Minoru, Miki, Takafumi, Uriu, Yoshitsugu, Nonaka, Mio, Bito, Haruhiko, Beedle, Aaron M., Mori, Emiko, Hara, Yuji, De Waard, Michel, Kanagawa, Motoi, Itakura, Makoto, Takahashi, Masami, Campbell, Kevin P., Mori, Yasuo
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2007
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2687938/
https://ncbi.nlm.nih.gov/pubmed/17496890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn1904
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