RIM1 and RIM2 redundantly determine Ca(2+) channel density and readily releasable pool size at a large hindbrain synapse

The localization and density of voltage-gated Ca(2+) channels at active zones are essential for the amount and kinetics of transmitter release at synapses. RIM proteins are scaffolding proteins at the active zone that bind to several other presynaptic proteins, including voltage-gated Ca(2+) channel...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Neurophysiol
Prif Awduron: Han, Yunyun, Babai, Norbert, Kaeser, Pascal, Südhof, Thomas C., Schneggenburger, Ralf
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Physiological Society 2014
Pynciau:
Cellular and Molecular Properties of Neurons
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4380487/
https://ncbi.nlm.nih.gov/pubmed/25343783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/jn.00488.2014
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