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Presynaptic Capacitance Measurements and Ca(2)(+) Uncaging Reveal Submillisecond Exocytosis Kinetics and Characterize the Ca(2)(+) Sensitivity of Vesicle Pool Depletion at a Fast CNS Synapse

The intracellular Ca(2+) sensitivity of synaptic vesicle fusion is an important determinant of transmitter release probability, but it is unknown for most CNS synapses. We combined whole-cell membrane capacitance measurements and Ca(2+) uncaging at the large calyx of Held nerve terminals to determin...

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Detalles Bibliográficos
Publicado en:J Neurosci
Main Authors: Wölfel, Markus, Schneggenburger, Ralf
Formato: Artigo
Idioma:Inglês
Publicado: Society for Neuroscience 2003
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6740656/
https://ncbi.nlm.nih.gov/pubmed/12904466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.23-18-07059.2003
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