RIM1 and RIM2 redundantly determine Ca(2+) channel density and readily releasable pool size at a large hindbrain synapse

The localization and density of voltage-gated Ca(2+) channels at active zones are essential for the amount and kinetics of transmitter release at synapses. RIM proteins are scaffolding proteins at the active zone that bind to several other presynaptic proteins, including voltage-gated Ca(2+) channel...

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Detalles Bibliográficos
Publicado en:J Neurophysiol
Autores principales: Han, Yunyun, Babai, Norbert, Kaeser, Pascal, Südhof, Thomas C., Schneggenburger, Ralf
Formato: Artigo
Lenguaje:Inglês
Publicado: American Physiological Society 2014
Materias:
Cellular and Molecular Properties of Neurons
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4380487/
https://ncbi.nlm.nih.gov/pubmed/25343783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/jn.00488.2014
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