RIM1 and RIM2 redundantly determine Ca(2+) channel density and readily releasable pool size at a large hindbrain synapse

The localization and density of voltage-gated Ca(2+) channels at active zones are essential for the amount and kinetics of transmitter release at synapses. RIM proteins are scaffolding proteins at the active zone that bind to several other presynaptic proteins, including voltage-gated Ca(2+) channel...

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Bibliographische Detailangaben
Veröffentlicht in:J Neurophysiol
Hauptverfasser: Han, Yunyun, Babai, Norbert, Kaeser, Pascal, Südhof, Thomas C., Schneggenburger, Ralf
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Physiological Society 2014
Schlagworte:
Cellular and Molecular Properties of Neurons
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4380487/
https://ncbi.nlm.nih.gov/pubmed/25343783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/jn.00488.2014
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