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RIM genes differentially contribute to organizing presynaptic release sites

Tight coupling of Ca(2+) channels to the presynaptic active zone is critical for fast synchronous neurotransmitter release. RIMs are multidomain proteins that tether Ca(2+) channels to active zones, dock and prime synaptic vesicles for release, and mediate presynaptic plasticity. Here, we use condit...

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書目詳細資料
Main Authors: Kaeser, Pascal S., Deng, Lunbin, Fan, Mingming, Südhof, Thomas C.
格式: Artigo
語言:Inglês
出版: National Academy of Sciences 2012
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3406861/
https://ncbi.nlm.nih.gov/pubmed/22753485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1209318109
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