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RIM Proteins Activate Vesicle Priming by Reversing Auto-Inhibitory Homodimerization of Munc13
At a synapse, the presynaptic active zone mediates synaptic vesicle exocytosis. RIM proteins are active-zone scaffolding molecules that – among others – mediate vesicle priming, and directly or indirectly interact with most other essential presynaptic proteins. In particular, the Zn(2+)-finger domai...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3063404/ https://ncbi.nlm.nih.gov/pubmed/21262469 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2011.01.005 |
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