Notch/HES1-mediated PARP1 activation: a cell type–specific mechanism for tumor suppression

Notch signaling plays both oncogenic and tumor suppressor roles, depending on cell type. In contrast to T-cell acute lymphoblastic leukemia (ALL), where Notch activation promotes leukemogenesis, induction of Notch signaling in B-cell ALL (B-ALL) leads to growth arrest and apoptosis. The Notch target...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Kannan, Sankaranarayanan, Fang, Wendy, Song, Guangchun, Mullighan, Charles G., Hammitt, Richard, McMurray, John, Zweidler-McKay, Patrick A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society of Hematology 2011
Gaiak:
Lymphoid Neoplasia
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3062299/
https://ncbi.nlm.nih.gov/pubmed/21224467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-12-253419
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak