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Phenyl Ring-Substituted Lobelane Analogs: Inhibition of [(3)H]Dopamine Uptake at the Vesicular Monoamine Transporter-2
Lobeline attenuates the behavioral effects of methamphetamine via inhibition of the vesicular monoamine transporter (VMAT2). To increase selectivity for VMAT2, chemically defunctionalized lobeline analogs, including lobelane, were designed to eliminate nicotinic acetylcholine receptor affinity. The...
में बचाया:
| मुख्य लेखकों: | , , , , |
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| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
The American Society for Pharmacology and Experimental Therapeutics
2011
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3061534/ https://ncbi.nlm.nih.gov/pubmed/20876747 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.110.172882 |
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