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Lobelane analogues as novel ligands for the vesicular monoamine transporter-2
A series of lobelane analogues has been synthesized and their structure–activity relationships at the vesicular monoamine transporter-2 (VMAT2) have been evaluated. The most potent analogues in this series were the cis-2,6-piperidino analogues, 25b, 27b, 28b, and 30b, with K(i) values ranging from 4...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3593046/ https://ncbi.nlm.nih.gov/pubmed/15911306 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2005.04.013 |
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