Lobelane analogues as novel ligands for the vesicular monoamine transporter-2

A series of lobelane analogues has been synthesized and their structure–activity relationships at the vesicular monoamine transporter-2 (VMAT2) have been evaluated. The most potent analogues in this series were the cis-2,6-piperidino analogues, 25b, 27b, 28b, and 30b, with K(i) values ranging from 4...

Full description

Saved in:
Bibliographic Details
Main Authors: Zheng, Guangrong, Dwoskin, Linda P., Deaciuc, Agripina G., Zhu, Jun, Jones, Marlon D., Crooks, Peter A.
Format: Artigo
Language:Inglês
Published: 2005
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3593046/
https://ncbi.nlm.nih.gov/pubmed/15911306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2005.04.013
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items