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Improved oral bioavailability in rats of SR13668, a novel anti-cancer agent
PURPOSE: SR13668, a bis-indole with potent activity in vitro and in vivo against various cancers and promising cancer chemopreventive activity, was found to have very low oral bioavailability, <1%, in rats during pilot pharmacokinetic studies. The objective of these studies was to better understa...
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| Main Authors: | , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3061244/ https://ncbi.nlm.nih.gov/pubmed/20623225 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00280-010-1395-9 |
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