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Pharmacokinetics, oral bioavailability, and metabolic profile of resveratrol and its dimethylether analog, pterostilbene, in rats

PURPOSE: Resveratrol (3,5,4′-trihydroxy-trans-stilbene) is a naturally occurring polyphenol with a broad range of possible health benefits, including anti-cancer activity. However, the biological activity of resveratrol may be limited by poor absorption and first-pass metabolism: only low plasma con...

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Detalhes bibliográficos
Main Authors: Kapetanovic, Izet M., Muzzio, Miguel, Huang, Zhihua, Thompson, Thomas N., McCormick, David L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3090701/
https://ncbi.nlm.nih.gov/pubmed/21116625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00280-010-1525-4
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