載入...

The p53 Inhibitor MDM2 Facilitates Sonic Hedgehog-Mediated Tumorigenesis and Influences Cerebellar Foliation

Disruption of cerebellar granular neuronal precursor (GNP) maturation can result in defects in motor coordination and learning, or in medulloblastoma, the most common childhood brain tumor. The Sonic Hedgehog (Shh) pathway is important for GNP proliferation; however, the factors regulating the exten...

全面介紹

Na minha lista:
書目詳細資料
Main Authors: Malek, Reem, Matta, Jennifer, Taylor, Natalie, Perry, Mary Ellen, Mendrysa, Susan M.
格式: Artigo
語言:Inglês
出版: Public Library of Science 2011
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3060880/
https://ncbi.nlm.nih.gov/pubmed/21437245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0017884
標簽: 添加標簽
沒有標簽, 成為第一個標記此記錄!