Loading...
The Regulation of the p53-mediated Stress Response by MDM2 and MDM4
Exquisite control of the activity of p53 is necessary for mammalian survival. Too much p53 is lethal, whereas too little permits tumorigenesis. MDM2 and MDM4 are structurally related proteins critical for the control of p53 activity during development, homeostasis, and the response to stress. These...
Saved in:
| Main Author: | |
|---|---|
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Cold Spring Harbor Laboratory Press
2010
|
| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2827903/ https://ncbi.nlm.nih.gov/pubmed/20182601 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a000968 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|