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Mdm2 Regulates p53 Independently of p19(ARF) in Homeostatic Tissues
Tumor suppressor proteins must be exquisitely regulated since they can induce cell death while preventing cancer. For example, the p19(ARF) tumor suppressor (p14(ARF) in humans) appears to stimulate the apoptotic function of the p53 tumor suppressor to prevent lymphomagenesis and carcinogenesis indu...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC303350/ https://ncbi.nlm.nih.gov/pubmed/14673154 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.1.186-191.2004 |
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