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Mdm2 Regulates p53 Independently of p19(ARF) in Homeostatic Tissues

Tumor suppressor proteins must be exquisitely regulated since they can induce cell death while preventing cancer. For example, the p19(ARF) tumor suppressor (p14(ARF) in humans) appears to stimulate the apoptotic function of the p53 tumor suppressor to prevent lymphomagenesis and carcinogenesis indu...

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Publicat a:Mol Cell Biol
Autors principals: O'Leary, Kathleen A., Mendrysa, Susan M., Vaccaro, Abram, Perry, Mary Ellen
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2004
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC303350/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14673154/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.24.1.186-191.2004
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