Mdm2 Regulates p53 Independently of p19(ARF) in Homeostatic Tissues

Tumor suppressor proteins must be exquisitely regulated since they can induce cell death while preventing cancer. For example, the p19(ARF) tumor suppressor (p14(ARF) in humans) appears to stimulate the apoptotic function of the p53 tumor suppressor to prevent lymphomagenesis and carcinogenesis indu...

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Bibliographische Detailangaben
Hauptverfasser: O'Leary, Kathleen A., Mendrysa, Susan M., Vaccaro, Abram, Perry, Mary Ellen
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2004
Schlagworte:
Cell Growth and Development
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC303350/
https://ncbi.nlm.nih.gov/pubmed/14673154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.1.186-191.2004
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