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Regulation of CCN2/CTGF Expression in the Nucleus Pulposus of the Intervertebral Disc: Role of Smad and AP1 Signaling
OBJECTIVE: To investigate TGFβ regulation of CTGF expression in cells of the nucleus pulposus. METHODS: Real Time RT-PCR and Western blot analysis was used to measure CTGF expression in the nucleus pulposus. Transfections were used to measure the effect of Smad2/3/7 and AP1on TGFβ mediated CTGF prom...
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| Glavni autori: | , , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2010
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3060556/ https://ncbi.nlm.nih.gov/pubmed/20222112 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.27445 |
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