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HIF Regulation of ANK Expression in Nucleus Pulposus Cells: Possible Implications in Controlling Dystrophic Mineralization in the Intervertebral Disc
OBJECTIVE: Since nucleus pulposus cells reside in hypoxia, we determined if expression of ANK, a pyrophosphate transporter, is regulated by the HIF proteins. METHODS: Quantitative RT-PCR and Western blot were used to measure ANK expression in nucleus pulposus cells. Transfections were performed to d...
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Main Authors: | , , , , , , , |
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格式: | Artigo |
語言: | Inglês |
出版: |
2010
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主題: | |
在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3065237/ https://ncbi.nlm.nih.gov/pubmed/20496369 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.27558 |
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