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Hypoxic Regulation of β1,3 Glucuronosyl Transferase-I (GlcAT-I) Expression in Nucleus Pulposus Cells of The Intervertebral Disc: Role of HIF Proteins
OBJECTIVE: The goal of the investigation was to study if hypoxia and HIF proteins regulate expression of GlcAT-I, a key enzyme in GAG synthesis in nucleus pulposus (NP) cells. METHODS: QRT-PCR and Western blot were used to measure GlcAT-I expression. Transfections were performed to determine the eff...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3125401/ https://ncbi.nlm.nih.gov/pubmed/21400481 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.30342 |
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