TGFβ Controls CCN3 Expression in Nucleus Pulposus Cells of the Intervertebral Disc

OBJECTIVE: To investigate TGFβ regulation of CCN3 expression in cells of the nucleus pulposus. METHODS: Real Time RT-PCR and Western blot analysis was used to measure CCN3 expression in the nucleus pulposus. Transfections were used to measure the effect of Smad3, MAPKs and AP1 on TGFβ mediated CCN3...

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Hauptverfasser: Tran, Cassie M., Smith, Harvey E., Symes, Aviva, Rittié, Laure, Perbal, Bernard, Shapiro, Irving M., Risbud, Makarand V.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3166549/
https://ncbi.nlm.nih.gov/pubmed/21618206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.30468
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