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TGFβ Controls CCN3 Expression in Nucleus Pulposus Cells of the Intervertebral Disc

OBJECTIVE: To investigate TGFβ regulation of CCN3 expression in cells of the nucleus pulposus. METHODS: Real Time RT-PCR and Western blot analysis was used to measure CCN3 expression in the nucleus pulposus. Transfections were used to measure the effect of Smad3, MAPKs and AP1 on TGFβ mediated CCN3...

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Detalhes bibliográficos
Main Authors: Tran, Cassie M., Smith, Harvey E., Symes, Aviva, Rittié, Laure, Perbal, Bernard, Shapiro, Irving M., Risbud, Makarand V.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3166549/
https://ncbi.nlm.nih.gov/pubmed/21618206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.30468
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