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SMAD3 Functions as a Transcriptional Repressor of Acid-Sensing Ion Channel 3 (ASIC3) in Nucleus Pulposus Cells of the Intervertebral Disc
The goal of this investigation was to study the regulation of acid-sensing ion channel (ASIC)3 expression by TGFβ in the nucleus pulposus cells of the intervertebral disc. Analysis of human nucleus pulposus tissue indicated decreased ASIC3 and elevated TGFβ expression in the degenerate state. In a p...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Amer Soc Bone & Mineral Res.
2008
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2684157/ https://ncbi.nlm.nih.gov/pubmed/18466073 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1359/JBMR.080502 |
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