טוען...
Design and control of acetylcholine receptor conformational change
Allosteric proteins use energy derived from ligand binding to promote a global change in conformation. The “gating” equilibrium constant of acetylcholine receptor-channels (AChRs) is influenced by ligands, mutations, and membrane voltage. We engineered AChRs to have specific values of this constant...
שמור ב:
| Main Authors: | , , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
National Academy of Sciences
2011
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3060238/ https://ncbi.nlm.nih.gov/pubmed/21368211 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1016617108 |
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