تحميل...

The Strain-Encoded Relationship between PrP(Sc) Replication, Stability and Processing in Neurons is Predictive of the Incubation Period of Disease

Prion strains are characterized by differences in the outcome of disease, most notably incubation period and neuropathological features. While it is established that the disease specific isoform of the prion protein, PrP(Sc), is an essential component of the infectious agent, the strain-specific rel...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Ayers, Jacob I., Schutt, Charles R., Shikiya, Ronald A., Aguzzi, Adriano, Kincaid, Anthony E., Bartz, Jason C.
التنسيق: Artigo
اللغة:Inglês
منشور في: Public Library of Science 2011
الموضوعات:
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC3060105/
https://ncbi.nlm.nih.gov/pubmed/21437239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1001317
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