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Transition of the prion protein from a structured cellular form (PrP(C)) to the infectious scrapie agent (PrP(Sc))
Prion diseases in mammals are caused by a conformational transition of the cellular prion protein from its native conformation (PrP(C)) to a pathological isoform called “prion protein scrapie” (PrP(Sc)). A molecular level of understanding of this conformational transition will be helpful in unveilin...
में बचाया:
| में प्रकाशित: | Protein Sci |
|---|---|
| मुख्य लेखकों: | , , , |
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
John Wiley & Sons, Inc.
2019
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6863700/ https://ncbi.nlm.nih.gov/pubmed/31583788 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.3735 |
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