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PrP(Sc) formation and clearance as determinants of prion tropism

Prion strains are characterized by strain-specific differences in neuropathology but can also differ in incubation period, clinical disease, host-range and tissue tropism. The hyper (HY) and drowsy (DY) strains of hamster-adapted transmissible mink encephalopathy (TME) differ in tissue tropism and s...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Shikiya, Ronald A., Langenfeld, Katie A., Eckland, Thomas E., Trinh, Jonathan, Holec, Sara A. M., Mathiason, Candace K., Kincaid, Anthony E., Bartz, Jason C.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5386299/
https://ncbi.nlm.nih.gov/pubmed/28355274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006298
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