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Optimizing Endothelial Targeting by Modulating the Antibody Density and Particle Concentration of Anti-ICAM Coated Carriers
Targeting of drug carriers to cell adhesion molecules expressed on endothelial cells (ECs) may improve treatment of diseases involving the vascular endothelium. This is the case for carriers targeted to intercellular adhesion molecule 1 (ICAM-1), an endothelial surface protein overexpressed in many...
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| Autores principales: | , , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2010
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3059751/ https://ncbi.nlm.nih.gov/pubmed/21047540 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2010.10.025 |
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