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Effect of flow on endothelial endocytosis of nanocarriers targeted to ICAM-1

Delivery of drugs into the endothelium by nanocarriers targeted to endothelial determinants may improve treatment of vascular maladies. This is the case for intercellular adhesion molecule 1 (ICAM-1), a glycoprotein overexpressed on endothelial cells (ECs) in many pathologies. ICAM-1-targeted nanoca...

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Bibliographic Details
Main Authors: Bhowmick, Tridib, Berk, Erik, Cui, Xiumin, Muzykantov, Vladimir R., Muro, Silvia
Format: Artigo
Language:Inglês
Published: 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3274617/
https://ncbi.nlm.nih.gov/pubmed/21951807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2011.09.067
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