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Transport of Nanocarriers Across Gastrointestinal Epithelial Cells by a New Transcellular Route Induced by Targeting ICAM-1

Bioavailability of oral drugs, particularly large hydrophilic agents, is often limited by poor adhesion and transport across gastrointestinal (GI) epithelial cells. Drug delivery systems, such as sub-micrometer polymer carriers (nanocarriers, NCs) coupled to affinity moieties that target GI surface...

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Hlavní autoři: Ghaffarian, Rasa, Bhowmick, Tridib, Muro, Silvia
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3462239/
https://ncbi.nlm.nih.gov/pubmed/22698938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2012.06.007
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