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Intertwined Mechanisms Define Transport of Anti-ICAM Nanocarriers Across the Endothelium and Brain Delivery of a Therapeutic Enzyme

The interaction of drug delivery systems with tissues is key for their application. An example is drug carriers targeted to endothelial barriers, which can be transported to intra-endothelial compartments (lysosomes) or transcellularly released at the tissue side (transcytosis). Although carrier tar...

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Detalhes bibliográficos
Publicado no:J Control Release
Main Authors: Manthe, Rachel L., Loeck, Maximilian, Bhowmick, Tridib, Solomon, Melani, Muro, Silvia
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7720842/
https://ncbi.nlm.nih.gov/pubmed/32389778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2020.05.009
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