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Biodistribution and endocytosis of ICAM-1-targeting antibodies versus nanocarriers in the gastrointestinal tract in mice

Drug delivery to the gastrointestinal (GI) tract is key for improving treatment of GI maladies, developing oral vaccines, and facilitating drug transport into circulation. However, delivery of formulations to the GI tract is hindered by pH changes, degradative enzymes, mucus, and peristalsis, leadin...

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Detalhes bibliográficos
Main Authors: Mane, Viraj, Muro, Silvia
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3418107/
https://ncbi.nlm.nih.gov/pubmed/22915850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S34105
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