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Targeting, Endocytosis, and Lysosomal Delivery of Active Enzymes to Model Human Neurons by ICAM-1-Targeted Nanocarriers

PURPOSE: Delivery of therapeutics to neurons is paramount to treat neurological conditions, including many lysosomal storage disorders. However, key aspects of drug-carrier behavior in neurons are relatively unknown: the occurrence of non-canonical endocytic pathways (present in other cells); whethe...

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Publicado en:Pharm Res
Main Authors: Hsu, Janet, Hoenicka, Janet, Muro, Silvia
Formato: Artigo
Idioma:Inglês
Publicado: 2014
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4973512/
https://ncbi.nlm.nih.gov/pubmed/25319100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-014-1531-z
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