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ICAM-1 Targeting, Intracellular Trafficking, and Functional Activity of Polymer Nanocarriers Coated with a Fibrinogen-Derived Peptide for Lysosomal Enzyme Replacement

Enzyme replacement is a viable treatment for diseases caused by genetic deficiency of lysosomal enzymes. However, suboptimal access of enzymes to target sites limits this strategy. Polymer nanocarriers (NCs) coated with antibody against intercellular adhesion molecule 1 (ICAM-1), a protein overexpre...

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Bibliographische Detailangaben
Veröffentlicht in:J Drug Target
Hauptverfasser: Garnacho, Carmen, Muro, Silvia
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5828777/
https://ncbi.nlm.nih.gov/pubmed/28665212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/1061186X.2017.1349771
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