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Optimizing Endothelial Targeting by Modulating the Antibody Density and Particle Concentration of Anti-ICAM Coated Carriers

Targeting of drug carriers to cell adhesion molecules expressed on endothelial cells (ECs) may improve treatment of diseases involving the vascular endothelium. This is the case for carriers targeted to intercellular adhesion molecule 1 (ICAM-1), an endothelial surface protein overexpressed in many...

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Detalhes bibliográficos
Main Authors: Calderon, Andres, Bhowmick, Tridib, Leferovich, John, Burmann, Bahrat, Pichette, Benjamin, Muzykantov, Vladimir, Eckmann, David, Muro, Silvia
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3059751/
https://ncbi.nlm.nih.gov/pubmed/21047540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2010.10.025
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