Optimizing Endothelial Targeting by Modulating the Antibody Density and Particle Concentration of Anti-ICAM Coated Carriers

Targeting of drug carriers to cell adhesion molecules expressed on endothelial cells (ECs) may improve treatment of diseases involving the vascular endothelium. This is the case for carriers targeted to intercellular adhesion molecule 1 (ICAM-1), an endothelial surface protein overexpressed in many...

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Main Authors: Calderon, Andres, Bhowmick, Tridib, Leferovich, John, Burmann, Bahrat, Pichette, Benjamin, Muzykantov, Vladimir, Eckmann, David, Muro, Silvia
Format: Artigo
Jezik:Inglês
Izdano: 2010
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3059751/
https://ncbi.nlm.nih.gov/pubmed/21047540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2010.10.025
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