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Analysis of PKR-RNA interactions by sedimentation velocity

PKR is an interferon-induced kinase that plays a pivotal role in the innate immunity pathway for defense against viral infection. PKR is activated to undergo autophosphorylation upon binding to RNAs that contain duplex regions. Some highly structured viral RNAs do not activate and function as PKR in...

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Bibliografische gegevens
Hoofdauteurs: Wong, C. Jason, Launer-Felty, Katherine, Cole, James L.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2011
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3058617/
https://ncbi.nlm.nih.gov/pubmed/21195224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/B978-0-12-381268-1.00003-3
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