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Structural Analysis of Adenovirus VAI RNA Defines the Mechanism of Inhibition of PKR

Protein kinase R (PKR) is activated by dsRNA produced during virus replication and plays a major role in the innate immunity response to virus infection. In response, viruses have evolved multiple strategies to evade PKR. Adenovirus virus-associated RNA-I (VAI) is a short, noncoding transcript that...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Biophys J
Päätekijät: Launer-Felty, Katherine, Wong, C. Jason, Cole, James L.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: The Biophysical Society 2015
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4317563/
https://ncbi.nlm.nih.gov/pubmed/25650941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2014.12.014
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