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Magnesium-Dependent Interaction of PKR with Adenovirus VAI RNA

PKR is an interferon-induced kinase that plays a pivotal role in the innate immunity pathway for defense against viral infection. PKR is activated to undergo autophosphorylation upon binding to RNAs that contain duplex regions. Activated PKR phosphorylates the alpha subunit of eukaryotic initiation...

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Detalhes bibliográficos
Main Authors: Launer-Felty, Katherine, Wong, C. Jason, Wahid, Ahmed M., Conn, Graeme L., Cole, James L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2980848/
https://ncbi.nlm.nih.gov/pubmed/20713064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2010.08.015
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