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Analysis of PKR-RNA interactions by sedimentation velocity
PKR is an interferon-induced kinase that plays a pivotal role in the innate immunity pathway for defense against viral infection. PKR is activated to undergo autophosphorylation upon binding to RNAs that contain duplex regions. Some highly structured viral RNAs do not activate and function as PKR in...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3058617/ https://ncbi.nlm.nih.gov/pubmed/21195224 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/B978-0-12-381268-1.00003-3 |
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