A portable RNA sequence whose recognition by a synthetic antibody facilitates structural determination
RNA crystallization and phasing represent major bottlenecks in RNA structure determination. Seeking to exploit antibody fragments as RNA crystallization chaperones, we have used an arginine-enriched synthetic Fab library displayed on phage to obtain Fabs against the class I ligase ribozyme. We solve...
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| Główni autorzy: | , , , , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
2010
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3058332/ https://ncbi.nlm.nih.gov/pubmed/21151117 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.1945 |
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