Synthetic antibodies for specific recognition and crystallization of structured RNA

Antibodies that bind protein antigens are indispensable in biochemical research and modern medicine. However, knowledge of RNA-binding antibodies and their application in the ever-growing RNA field is lacking. Here we have developed a robust approach using a synthetic phage-display library to select...

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Autors principals: Ye, Jing-Dong, Tereshko, Valentina, Frederiksen, John K., Koide, Akiko, Fellouse, Frederic A., Sidhu, Sachdev S., Koide, Shohei, Kossiakoff, Anthony A., Piccirilli, Joseph A.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2008
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2224236/
https://ncbi.nlm.nih.gov/pubmed/18162543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0709082105
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